Control of oxidative phosphorylation in muscle.

There is no single answer to the question ‘How is oxidative phosphorylation controlled (or regulated)?’. Control varies with conditions, and is shared between at least two different reactions under all conditions. However, it is possible to provide a simple quantitative description of the control using control analysis. Hecause of the kinetics of all three blocks of reactions involved, oxidation and phosphorylation are controlled differently. This has important consequences for the regulation of the rate and of the efficiency of oxidative phosphorylation. 762